B7H3, also known as CD276, is a protein belonging to the B7 family of immune regulatory molecules. It is a transmembrane protein that plays a significant role in immune regulation and tumor immunotherapy. B7H3 can exist in different structural forms, with variations such as 4IG (containing 4 immunoglobulin domains) and 2IG (containing 2 immunoglobulin domains).

This protein is known to be highly expressed in various tumors and is closely associated with tumor development, progression, and prognosis. In the context of tumor immunotherapy, B7H3 serves as an important target due to its ability to modulate T cell responses. Inhibiting B7H3 protein can enhance the killing capacity of T cells against tumor cells, thereby improving the effectiveness of cancer treatment.

Overall, B7H3 plays a crucial role in immune regulation, immune response modulation, and tumor immune evasion. Understanding the mechanisms involving B7H3 protein can provide valuable insights into immunotherapy strategies and tumor development.

高纯度、高活性、低内毒素、高批间一致性

SDS-PAGE

Figure 1.On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA

Figure 2. Biotinylated Human CD276(B7H3 2Ig) Protein, His-Avi Tag) was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-CD276(B7H3) hIgG1 Reference Antibody were added.

-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。